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<!DOCTYPE html>
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<title>Slimane's Web page</title>
<meta name="description" content="In this personal web page you will find full descritpion of my scientific cursus and also my publications and interests. as a bioinformatician I'll try to give some tutorials about my routine day in fron of my workstation in dealing with biological data especially DNA sequences"/>
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<div class="h2 title">Slimane KHAYI, PhD</div>
<p style="color:white;font:bold;font-size:150%">Bioinformatician, Agrigenomist</p>
<a href="https://www.inra.org.ma" target="_blank" style="color: #1be810;font-size:150%">National Institute for Agricultural Research</a>
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<p>Hello! I'm Slimane KHAYI, a Bioinformatician and molecular biologist harnessing the genomic era
to answer biological questions. My interests are DNA and RNA, so I work on several organisms, across the tree of life,
that seems to be differents, Bacteria (Pectobacteriaceae), Fungi (Fusarium oxysporum f. sp. albedinis), Plants(Argania spinosa, Phoenix dactylifera), whereas these organisms are more similar to each other than we are to all bacteria!</p>
<p>Some biological questions that I'm working on could be formulated as ;What are the pieces of DNA that code the pathogenicity of FOA on the host? How and why do bacterial genomes change over time? What about the genome of the Moroccan endemic Argania spinosa?</p>
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BP. 6356, Rabat-Instituts 10101, Rabat, Morocco</div>
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<section>
<ol>
<li><a href="https://mra.asm.org/content/9/29/e00462-20" target="_blank"><b>Khayi, S</b>.; Khoulassa, S.; Gaboun, F. et al. Draft Genome Sequence of Fusarium oxysporum f. sp. albedinis Strain Foa 133, the Causal Agent of Bayoud Disease on Date Palm. <b>2020</b> Microbiol Resour Announc , 9 (29) e00462-20; DOI: 10.1128/MRA.00462-20</a></li><br>
<li><a href="https://www.mdpi.com/2076-2607/8/6/895/htm" target="_blank">Oulghazi, S.; Moumni, M.;<b>Khayi, S.</b>; Robic, K.; Sarfraz, S.; Lopez-Roques, C.; Vandecasteele, C.; Faure, D. Diversity of Pectobacteriaceae Species in Potato Growing Regions in Northern Morocco. Microorganisms <b>2020</b>, 8, 895..</a></li><br>
<li><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238458/" target="_blank" ><b>Khayi S,</b> Azza NE, Gaboun F et al.<b>(2020)</b> First draft genome assembly of the Argane tree (Argania spinosa) [version 2; peer review: 2 approved]. F1000Research 2020, 7:1310.</a></li><br>
<li><a href="https://mra.asm.org/content/9/20/e00189-20" target="_blank"><b>Khayi, S.</b>, Mentag, R., Jemo, M., <b>(2020)</b>. Draft Genome Sequence of Biological N2-Fixing Bacterium Rhizobium tropici A12, Isolated from Root Nodule of Tropical Soybean (Glycine max), TGx-1148 Variety.Microbiol Resour Announc 9:e00189-20.</a></li><br>
<li><a href="https://www.sciencedirect.com/science/article/pii/S1567134819303235" target="_blank">Drissi Touzani, C., Fellahi, S., Fassi Fihri, O., Gaboun, F., <b>Khayi, S.</b>, Mentag, R., Lico, C., Baschieri, S., El Houadfi, M., and Ducatez, M. <b>(2020)</b>. Complete genome analysis and time scale evolution of very virulent infectious bursal disease viruses isolated from recent outbreaks in Morocco. Infect. Genet. Evol. 77, 104097</a></li>
<br>
<li><a href="https://pubmed.ncbi.nlm.nih.gov/31223497/" target="_blank">Ed-Dra A, Filali FR, <b>Khayi, S.</b>, Oulghazi S, Bouchrif B, El Allaoui A, et al.<b>(2019)</b> Antimicrobial resistance, virulence genes, and genetic diversity of Salmonella enterica isolated from sausages. Eur J Microbiol Immunol. 2019;1–6.</a></li><br>
<li>Khayi, S, Blin, P, Chong TM, Robic, K, Chan K-G, Faure.D, « Complete Genome Sequences of the Plant Pathogens Dickeya Solani RNS 08.23.3.1.A and Dickeya Dianthicola RNS04.9 ». Genome Announcements 6, no 4 2018: e01447-17.<a href="https://doi.org/10.1128/genomeA.01447-17">link</a></li><br>
<li>Oulghazi S, Khayi S, Lafkih N, Massaoudi Y, El Karkouri A, El Hassouni M, et al. First Report of Dickeya dianthicola Causing Blackleg Disease on Potato in Morocco. Plant Disease. 2017;101:1671.<a href="https://apsjournals.apsnet.org/doi/abs/10.1094/PDIS-04-17-0548-PDN" target="_blank">link</a></li><br>
<li>Khayi S, Cigna J, Chong TM, Quêtu-Laurent A, Chan K-G, Hélias V, et al. Transfer of the potato plant isolates of Pectobacterium wasabiae to Pectobacterium parmentieri sp. nov. International Journal of Systematic and Evolutionary Microbiology. 2016;66:5379–83.</li><br>
<li>Khayi S, Raoul des Essarts Y, Quêtu-Laurent A, Moumni M, Hélias V, Faure D. Genomic overview of the phytopathogen Pectobacterium wasabiae strain RNS 08.42.1A suggests horizontal acquisition of quorum-sensing genes. Genetica. 2015;143:241–52.</li><br>
<li>Khayi S, Raoul des Essarts Y, Mondy S, Moumni M, Hélias V, Beury-Cirou A, et al. Draft Genome Sequences of the Three Pectobacterium-Antagonistic Bacteria Pseudomonas brassicacearum PP1-210F and PA1G7 and Bacillus simplex BA2H3: TABLE 1. Genome Announcements. 2015;3:e01497–14.</li><br>
<li>Khayi S, Blin P, Pédron J, Chong T-M, Chan K-G, Moumni M, et al. Population genomics reveals additive and replacing horizontal gene transfers in the emerging pathogen Dickeya solani. BMC Genomics. 2015;16:788.</li><br>
<li>Khayi S, Blin P, Chong TM, Chan K-G, Faure D. Complete genome anatomy of the emerging potato pathogen Dickeya solani type strain IPO 2222T. Standards in Genomic Sciences. 2016 [cited 2017 Sep 7];11. Available from: http://standardsingenomics.biomedcentral.com/articles/10.1186/s40793-016-0208-0 </li><br>
<li>Khayi S, Mondy S, Beury-Cirou A, Moumni M, Helias V, Faure D. Genome Sequence of the Emerging Plant Pathogen Dickeya solani Strain RNS 08.23.3.1A. Genome Announcements. 2014;2:e01270–13 – e01270–13.</li><br>
<li>Fellahi S, El Harrak M, Khayi S, Guerin J-L, Kuhn JH, El Houadfi M, et al. Phylogenetic analysis of avian infectious bronchitis virus isolates from Morocco: a retrospective study (1983 to 2014). Virologica Sinica. 2017;32:155–8.</li><br>
<li>Fellahi S, EL Harrak M, Ducatez M, Loutfi C, Koraichi SIS, Kuhn JH, Khayi S, et al. Phylogenetic analysis of avian infectious bronchitis virus S1 glycoprotein regions reveals emergence of a new genotype in Moroccan broiler chicken flocks. Virology Journal. 2015 [cited 2015 Aug 4];12. Available from: http://www.virologyj.com/content/12/1/116</li><br>
</ol>
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<div class="h4 text-center mb-4 title">Work Experience</div>
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<p>January 2017 - Present</p>
<div class="h5" ><a href="https://www.inra.org.ma" target="_blank">INRA</a></div>
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<div class="h5">Research Scientist</div>
<p>I'm currently working as researcher at the Moroccan National Institute for Agricultural Research (INRA). My current focus is on the genomics of endemic species Argania spinosa. We are taking advantages of the development of NGS technologies and genome-based approaches to highlight the genome patrimony of this precious species. In this context, we are addressing several issues such as molecular markers for important traits, conservation of the genetic resources.</p>
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<p>January 2016 - December 2016</p>
<div class="h5"><a href="https://www.i2bc.paris-saclay.fr" target="_blank">I2BC</a></div>
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<div class="h5">Postdoctoral Researcher</div>
<p>During my doctoral and postdoctoral stages, I worked on the soft rot pathogens Pectobacterium and Dickeya exploring multiple aspects such as genomics, evolution, virulence and ecology</p>
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<p>2012 - 2015</p>
<div class="h5">Joint Doctorate</div>
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<div class="h5">Doctorate in Computational and Molecular Biology</div>
<p class="category"><a href="https://www.universite-paris-saclay.fr/en" target="_blank">Université Paris-Saclay, Paris, France</a> & <a href="http://www.umi.ac.ma/?lang=en" target="_blank">Université Moulay Ismail, Meknès, Morocco</a></p>
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<p>2009 - 2011</p>
<div class="h5">Master's Degree</div>
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<div class="h5">Master of Biotechnology</div>
<p class="category"><a href="http://www.umi.ac.ma/?lang=en" target="_blank">Université Moulay Ismail, Meknès, Morocco</a></p>
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<p class="pb-2">Av. Mohamed Belarbi Alaoui BP. 6356, Rabat-Instituts 10101, Rabat, Morocco</p>
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