Additional parameters min_fract_pos
and min_cells_per_group
in perform_dge()
#180
Labels
enhancement
New feature or request
We are repeatedly asked to filter out lowly expressed genes before performing DGE analysis.
Currently, I only have a workaround by filtering the provided DGE results, but the correct way would be to filter them before applying the DGE test. Would it be possible to add such a parameter (e.g
min_fract_pos
) to the functionsperform_dge()
andget_de()
, so that a gene should be positive > min_fract_pos in at least one group.This parameter is routinely used in seurat FindMarkers(), see: https://www.rdocumentation.org/packages/Seurat/versions/2.3.0/topics/FindMarkers
PS: I would also include a
min_cells_per_group
inget_de()
, as it's already the case forperform_dge()
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