diff --git a/.github/workflows/build-image.yml b/.github/workflows/build-image.yml
index 6dd68c1273..b04e78b589 100644
--- a/.github/workflows/build-image.yml
+++ b/.github/workflows/build-image.yml
@@ -14,7 +14,15 @@ jobs:
   build:
     name: Build image
     runs-on: ubuntu-20.04
-
+    strategy:
+      matrix:
+        include:
+          - arch: arm64
+            image: bioconda-utils-build-env-cos7-aarch64
+            base_image: quay.io/condaforge/linux-anvil-aarch64
+          - arch: amd64
+            image: bioconda-utils-build-env-cos7
+            base_image: quay.io/condaforge/linux-anvil-cos7-x86_64
     steps:
     - uses: actions/checkout@v3
       with:
@@ -28,11 +36,19 @@ jobs:
         # printf %s "::set-output name=tag::${tag#v}"
         printf %s "tag=${tag#v}" >> $GITHUB_OUTPUT
 
+    - name: Install qemu dependency
+      run: |
+        sudo apt-get update
+        sudo apt-get install -y qemu-user-static
+
     - name: Build image
       id: buildah-build
       uses: redhat-actions/buildah-build@v2
       with:
-        image: bioconda-utils-build-env-cos7
+        image: ${{ matrix.image }}
+        arch: ${{ matrix.arch }}
+        build-args: |
+          BASE_IMAGE=${{ matrix.base_image }}
         tags: >-
           latest
           ${{ steps.get-tag.outputs.tag }}
diff --git a/.github/workflows/release-please.yml b/.github/workflows/release-please.yml
index 86cb768a19..9c4c3d5e26 100644
--- a/.github/workflows/release-please.yml
+++ b/.github/workflows/release-please.yml
@@ -8,6 +8,15 @@ name: release-please
 jobs:
   release-please:
     runs-on: ubuntu-latest
+    strategy:
+      matrix:
+        include:
+          - arch: arm64
+            image: bioconda-utils-build-env-cos7-aarch64
+            base_image: quay.io/condaforge/linux-anvil-aarch64
+          - arch: amd64
+            image: bioconda-utils-build-env-cos7
+            base_image: quay.io/condaforge/linux-anvil-cos7-x86_64
     steps:
 
       - uses: GoogleCloudPlatform/release-please-action@v2
@@ -28,12 +37,20 @@ jobs:
           tag=${{ steps.release.outputs.tag_name }}
           printf %s "::set-output name=tag::${tag#v}"
 
+      - name: Install qemu dependency
+        run: |
+          sudo apt-get update
+          sudo apt-get install -y qemu-user-static
+
       - name: Build Image
         if: ${{ steps.release.outputs.release_created }}
         id: buildah-build
         uses: redhat-actions/buildah-build@v2
         with:
-          image: bioconda-utils-build-env-cos7
+          image: ${{ matrix.image }}
+          arch: ${{ matrix.arch }}
+          build-args: |
+            BASE_IMAGE=${{ matrix.base_image }}
           tags: >-
             latest
             ${{ steps.get-tag.outputs.tag }}
diff --git a/Dockerfile b/Dockerfile
index 251af127dd..f509b73c3b 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -1,4 +1,9 @@
-FROM quay.io/condaforge/linux-anvil-cos7-x86_64 as base
+# Specify the base image to support multi-arch images, such as
+# - 'quay.io/condaforge/linux-anvil-aarch64' for Linux aarch64
+# - 'quay.io/condaforge/linux-anvil-cos7-x86_64' for Linux x86_64
+ARG BASE_IMAGE=quay.io/condaforge/linux-anvil-cos7-x86_64
+
+FROM ${BASE_IMAGE} as base
 
 # Copy over C.UTF-8 locale from our base image to make it consistently available during build.
 COPY --from=quay.io/bioconda/base-glibc-busybox-bash /usr/lib/locale/C.UTF-8 /usr/lib/locale/C.UTF-8
diff --git a/bioconda_utils/bioconda_utils-requirements.txt b/bioconda_utils/bioconda_utils-requirements.txt
index a796722116..3cd499b43b 100644
--- a/bioconda_utils/bioconda_utils-requirements.txt
+++ b/bioconda_utils/bioconda_utils-requirements.txt
@@ -9,16 +9,16 @@ boa=0.9.*
 conda-build=3.21.8
 conda-verify=3.1.*
 argh=0.26.*          # CLI
-colorlog=3.1.*       # Logging
+colorlog=4.8.*       # Logging
 tqdm>=4.26           # Progress monitor
 ruamel_yaml=0.15.*   # Recipe YAML parsing
 pyaml=17.12.*        # Faster YAML parser (deprecate?)
 networkx=2.*
-pandas=0.23.*
+pandas=1.4.*
 numpy=1.19.*         # Avoid breaking pandas on OSX
 libblas=*=*openblas  # Avoid large mkl package (pulled in by pandas)
 boltons=18.*
-jsonschema=2.6.*     # JSON schema verification
+jsonschema=3.2.*     # JSON schema verification
 simplejson           # Used by bioconda bot worker (NEEDED?)
 pyopenssl>=22.1      # Stay compatible with cryptography
 
@@ -28,11 +28,11 @@ conda-forge-pinning=2022.08.25.15.20.42
 # tools
 anaconda-client=1.6.*  # anaconda_upload
 involucro=1.1.*        # mulled test and container build
-skopeo=0.1.35          # docker upload
+skopeo=1.11.*          # docker upload
 git=2.*                # well - git
 
 # hosters - special regex not supported by RE
-regex=2018.08.29
+regex=2022.7.9
 
 # asyncio
 aiohttp=3.8.*      # HTTP lib
@@ -51,7 +51,7 @@ gidgethub=3.0.*           # githubhandler
 pyjwt>=2.4.0              # githubhandler (JWT signing), needs >=2.4.0, CVE-2022-29217
 
 # unknown
-beautifulsoup4=4.6.*
+beautifulsoup4=4.8.*
 galaxy-lib>=18.9.1
 jinja2>=2.10.1,<3
 markupsafe<2.1           # markupsafe 2.1 breaks jinja2
@@ -69,4 +69,4 @@ graphviz
 requests=2.22.*
 
 # merge handling
-pygithub
\ No newline at end of file
+pygithub
diff --git a/bioconda_utils/cli.py b/bioconda_utils/cli.py
index b74701e4eb..7a66147723 100644
--- a/bioconda_utils/cli.py
+++ b/bioconda_utils/cli.py
@@ -426,13 +426,16 @@ def do_lint(recipe_folder, config, packages="*", cache=None, list_checks=False,
      than one worker, then make sure to give each a different offset!''')
 @arg('--keep-old-work', action='store_true', help='''Do not remove anything
 from environment, even after successful build and test.''')
+@arg('--docker-base-image', help='''Name of base image that can be used in
+     Dockerfile template.''')
 @enable_logging()
 def build(recipe_folder, config, packages="*", git_range=None, testonly=False,
           force=False, docker=None, mulled_test=False, build_script_template=None,
           pkg_dir=None, anaconda_upload=False, mulled_upload_target=None,
           build_image=False, keep_image=False, lint=False, lint_exclude=None,
           check_channels=None, n_workers=1, worker_offset=0, keep_old_work=False,
-          mulled_conda_image=pkg_test.MULLED_CONDA_IMAGE):
+          mulled_conda_image=pkg_test.MULLED_CONDA_IMAGE,
+          docker_base_image='quay.io/bioconda/bioconda-utils-build-env-cos7:{}'.format(VERSION.replace('+', '_'))):
     cfg = utils.load_config(config)
     setup = cfg.get('setup', None)
     if setup:
@@ -458,6 +461,7 @@ def build(recipe_folder, config, packages="*", git_range=None, testonly=False,
             use_host_conda_bld=use_host_conda_bld,
             keep_image=keep_image,
             build_image=build_image,
+            docker_base_image=docker_base_image
         )
     else:
         docker_builder = None
diff --git a/bioconda_utils/docker_utils.py b/bioconda_utils/docker_utils.py
index a43d864646..b6d21e8bed 100644
--- a/bioconda_utils/docker_utils.py
+++ b/bioconda_utils/docker_utils.py
@@ -60,6 +60,8 @@
 import conda
 import conda_build
 
+from conda import exports as conda_exports
+
 from . import utils
 from . import __version__
 
@@ -90,9 +92,10 @@
 #
 # Note that if the directory didn't exist on the host, then the staging area
 # will exist in the container but will be empty.  Channels expect at least
-# a linux-64 and noarch directory within that directory, so we make sure it
-# exists before adding the channel.
+# a linux-64/linux-aarch64 and noarch directory within that directory, so we
+# make sure it exists before adding the channel.
 mkdir -p {self.container_staging}/linux-64
+mkdir -p {self.container_staging}/linux-aarch64
 mkdir -p {self.container_staging}/noarch
 touch {self.container_staging}/noarch/repodata.json
 conda config --add channels file://{self.container_staging} 2> >(
@@ -442,8 +445,9 @@ def build_recipe(self, recipe_dir, build_args, env, noarch=False):
 
         # Write build script to tempfile
         build_dir = os.path.realpath(tempfile.mkdtemp())
+        # conda_exports.subdir is {platform}-{arch} like: 'linux-64' 'linux-aarch64'
         script = self.build_script_template.format(
-            self=self, arch='noarch' if noarch else 'linux-64')
+            self=self, arch='noarch' if noarch else conda_exports.subdir)
         with open(os.path.join(build_dir, 'build_script.bash'), 'w') as fout:
             fout.write(script)
         build_script = fout.name
diff --git a/bioconda_utils/utils.py b/bioconda_utils/utils.py
index 17ab445326..2db32ad463 100644
--- a/bioconda_utils/utils.py
+++ b/bioconda_utils/utils.py
@@ -49,6 +49,7 @@
 
 from conda_build import api
 from conda.exports import VersionOrder
+from conda.exports import subdir as conda_subdir
 from boa.cli.mambabuild import prepare as insert_mambabuild
 
 from jsonschema import validate
@@ -1116,7 +1117,16 @@ def _filter_existing_packages(metas, check_channels):
                 new_metas.append(meta)
             else:
                 existing_metas.append(meta)
-        for divergent_build in (existing_pkg_builds - set(build_meta.keys())):
+        # Filter the existing_pkg_builds according to the native CPU architecture to avoid
+        # inaccurate divergent build results.
+        #
+        # For example, when a package has only `linux-64` arch type package, if we
+        # build on aarch64 machine, the `divergent_builds` will wrongly include the linux-64
+        # one, we need to filter the non-native CPU architecture versions.
+        native_pkg_builds = {
+            x for x in existing_pkg_builds if x.subdir in (conda_subdir, 'noarch')
+        }
+        for divergent_build in (native_pkg_builds - set(build_meta.keys())):
             divergent_builds.add(
                 '-'.join((pkg_key[0], pkg_key[1], divergent_build[1])))
     return new_metas, existing_metas, divergent_builds