diff --git a/tests/conftest.py b/tests/conftest.py
index c4656cb7..81176c7e 100644
--- a/tests/conftest.py
+++ b/tests/conftest.py
@@ -29,6 +29,7 @@ def pytest_collection_modifyitems(items):
         "test_merge",
         "test_database",
         "test_query",
+        "test_endpoints",
         "test_emit_warnings",
     ]
     # remember to add new test modules to the order constant:
diff --git a/tests/unit/test_endpoints.py b/tests/unit/test_endpoints.py
new file mode 100644
index 00000000..0ca4f7b0
--- /dev/null
+++ b/tests/unit/test_endpoints.py
@@ -0,0 +1,42 @@
+"""Perform basic tests of endpoint branches.
+We already have tests and data validation to ensure correctness of the underlying
+response objects -- here, we're checking for bad branch logic and for basic assurances
+that routes integrate correctly with query methods.
+"""
+import pytest
+from fastapi.testclient import TestClient
+
+from disease.main import app
+
+
+@pytest.fixture(scope="module")
+def api_client():
+    """Provide test client fixture."""
+    return TestClient(app)
+
+
+def test_search(api_client):
+    """Test /search endpoint."""
+    response = api_client.get("/disease/search?q=neuroblastoma")
+    assert response.status_code == 200
+    assert (
+        response.json()["source_matches"]["Mondo"]["records"][0]["concept_id"]
+        == "mondo:0005072"
+    )
+
+    response = api_client.get("/disease/search?q=neuroblastoma&incl=sdkl")
+    assert response.status_code == 422
+
+
+def test_normalize(api_client):
+    """Test /normalize endpoint."""
+    response = api_client.get("/disease/normalize?q=neuroblastoma")
+    assert response.status_code == 200
+    assert response.json()["normalized_id"] == "ncit:C3270"
+
+
+def test_normalize_unmerged(api_client):
+    """Test /normalize_unmerged endpoint."""
+    response = api_client.get("/disease/normalize_unmerged?q=neuroblastoma")
+    assert response.status_code == 200
+    assert response.json()["normalized_concept_id"] == "ncit:C3270"