Calibrating using pureCN causes multiple segments to go -10

[shashwatsahay]

Calibrating segments with pureCN output causes output to have many segement copy ratio to go to -10

uncalibrated

calibrated

Also For a particular sample I have oversegmentation any ideas how to resolve this

[shashwatsahay]

Have solved the -10 log values these are due to me not dropping segments with low coverage.

Any recommendation fo noisy sample