diff --git a/depends/README.md b/depends/README.md
index 6dbe3655459e7d..dc5d4da7ce4ff1 100644
--- a/depends/README.md
+++ b/depends/README.md
@@ -12,14 +12,17 @@ For example:
 
     make HOST=x86_64-w64-mingw32 -j4
 
-A prefix will be generated that's suitable for plugging into Bitcoin's
-configure. In the above example, a dir named x86_64-w64-mingw32 will be
+**Bitcoin's configure script by default will ignore the depends output.** In
+order for it to pick up libraries, tools, and settings from the depends build,
+you must point it at the appropriate `--prefix` directory generated by the
+build. In the above example, a prefix dir named x86_64-w64-mingw32 will be
 created. To use it for Bitcoin:
 
     ./configure --prefix=`pwd`/depends/x86_64-w64-mingw32
 
 Common `host-platform-triplets` for cross compilation are:
 
+- `x86_64-pc-linux-gnu` for x86 Linux
 - `x86_64-w64-mingw32` for Win64
 - `x86_64-apple-darwin14` for macOS
 - `arm-linux-gnueabihf` for Linux ARM 32 bit