diff --git a/src/fileseq/filesequence.py b/src/fileseq/filesequence.py
index 1b61963..0609e45 100644
--- a/src/fileseq/filesequence.py
+++ b/src/fileseq/filesequence.py
@@ -814,6 +814,8 @@ def yield_sequences_in_list(
             :obj:`FileSequence`:
         """
         seqs = {}
+        variant_seq = 0
+        variant_single = 1
         if allow_subframes:
             _check = cls.DISK_SUB_RE.match
         else:
@@ -839,7 +841,7 @@ def yield_sequences_in_list(
                     except decimal.DecimalException:
                         continue
                 _, _, subframe = frame.partition(".")
-                key = (dirname, basename, ext, len(subframe))
+                key = (dirname, basename, ext, len(subframe), variant_seq)
                 seqs.setdefault(key, frames).add(frame)
 
         else:
@@ -849,9 +851,9 @@ def yield_sequences_in_list(
                     continue
                 if frame:
                     _, _, subframe = frame.partition(".")
-                    key = (dirname, basename, ext, len(subframe))
+                    key = (dirname, basename, ext, len(subframe), variant_seq)
                 else:
-                    key = (dirname, basename, ext, 0)
+                    key = (dirname, basename, ext, 0, variant_single)
                 seqs.setdefault(key, set())
                 if frame:
                     seqs[key].add(frame)
@@ -896,7 +898,8 @@ def frames_to_seq(frames, pad_length, decimal_places):
             finish_new_seq(seq)
             return seq
 
-        for (dirname, basename, ext, decimal_places), frames in iteritems(seqs):
+        for parts, frames in iteritems(seqs):
+            (dirname, basename, ext, decimal_places) = parts[:4]
             # Short-circuit logic if we do not have multiple frames, since we
             # only need to build and return a single simple sequence
             if not frames:
diff --git a/test/test_unit.py b/test/test_unit.py
index 5ce8a06..53e1106 100755
--- a/test/test_unit.py
+++ b/test/test_unit.py
@@ -1361,6 +1361,22 @@ def test_yield_sequences_in_list_pad_style(self):
         self.assertEqual(fileseq.PAD_STYLE_HASH1, actual.padStyle())
         self.assertEqual(4, actual.zfill())
 
+    def test_yield_sequences_in_list_frame_no_frame(self):
+        paths = [
+            'frame_no_frame/file02.jpg',
+            'frame_no_frame/file.jpg',
+            'frame_no_frame/name.jpg',
+        ]
+
+        expects = [
+            'frame_no_frame/file2@@.jpg',
+            'frame_no_frame/file.jpg',
+            'frame_no_frame/name.jpg',
+        ]
+        actual = {str(fs) for fs in FileSequence.yield_sequences_in_list(paths)}
+        for expect in expects:
+            self.assertIn(expect, actual)
+
     def testIgnoreFrameSetStrings(self):
         for char in "xy:,".split():
             fs = FileSequence("/path/to/file{0}1-1x1#.exr".format(char))