From 82028a8e39b3ccbced8208d2592e2c09dcdcbb8e Mon Sep 17 00:00:00 2001 From: Sebastian Duesing Date: Fri, 6 Oct 2023 12:54:05 -0500 Subject: [PATCH] Adds two iedb assays --- src/ontology/modules/epitope-assays.owl | 64 +++++++++++++++++++++++ src/ontology/templates/epitope-assays.tsv | 2 + 2 files changed, 66 insertions(+) diff --git a/src/ontology/modules/epitope-assays.owl b/src/ontology/modules/epitope-assays.owl index 4f4ee941..15c3a55c 100644 --- a/src/ontology/modules/epitope-assays.owl +++ b/src/ontology/modules/epitope-assays.owl @@ -22784,6 +22784,70 @@ + + + + + + + + + + + + + + + + + + + + + + + + An electron-microscopy 3D molecular structure determination assay that characterizes the 3-dimensional molecular structrue of a T cell epitope:MHC:TCR complex. + PERSON:Randi Vita, Sebastian Duesing, Bjoern Peters + IEDB + 3D structure|electron microscopy + electron microscopy assay determining the 3D structure of a T cell epitope:MHC:TCR complex + + + + + + + + + + + + + + + + + + + + + + + + + + + + An electron-microscopy 3D molecular structure determination assay that characterizes the 3-dimensional molecular structrue of a MHC:ligand complex. + PERSON:Randi Vita, Sebastian Duesing, Bjoern Peters + IEDB + 3D structure|electron microscopy + electron microscopy assay determining the 3D structure of a MHC:ligand complex + + + + diff --git a/src/ontology/templates/epitope-assays.tsv b/src/ontology/templates/epitope-assays.tsv index 18012d47..728f93dd 100644 --- a/src/ontology/templates/epitope-assays.tsv +++ b/src/ontology/templates/epitope-assays.tsv @@ -500,6 +500,8 @@ OBI:0003486 intracellular cytokine staining assay measuring epitope specific int OBI:0003487 ELISA measuring epitope specific interleukin-25 production by T cells IL-25 release|ELISA An enzyme-linked immunosorbent assay that detects interleukin-25 production by T cells. IEDB IEDB equivalent enzyme-linked immunosorbent assay ('interleukin-25 production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) OBI:0003488 cell culture analyte detection bioassay measuring epitope specific tumor necrosis factor superfamily cytokine production by T cells TNF release|bioassay A reporter cell line analyte detection bioassay that detects tumor necrosis factor superfamily cytokine production by T cells. IEDB IEDB equivalent reporter cell line analyte detection bioassay ('tumor necrosis factor superfamily cytokine production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) OBI:0003602 quartz crystal microbalance assay measuring the dissociation constant [KD] of a B cell epitope:antibody complex quartz crystal microbalance measuring the dissociation constant [KD] of a B cell epitope:antibody complex QCM measuring KD dissociation constant KD|quartz crystal microbalance|nM A quartz crystal microbalance assay that measures the dissociation constant [KD] of an antigen binding with an antibody. IEDB Randi Vita|Bjoern Peters|Sebastian Duesing subclass quartz crystal microbalance assay equilibrium dissociation constant (KD) immunoglobulin binding to epitope nanomolar +OBI:0003612 electron microscopy assay determining the 3D structure of a T cell epitope:MHC:TCR complex 3D structure|electron microscopy An electron-microscopy 3D molecular structure determination assay that characterizes the 3-dimensional molecular structrue of a T cell epitope:MHC:TCR complex. IEDB PERSON:Randi Vita, Sebastian Duesing, Bjoern Peters equivalent electron-microscopy 3D molecular structure determination assay 3D structural organization datum epitope:MHC:TCR complex +OBI:0003613 electron microscopy assay determining the 3D structure of a MHC:ligand complex 3D structure|electron microscopy An electron-microscopy 3D molecular structure determination assay that characterizes the 3-dimensional molecular structrue of a MHC:ligand complex. IEDB PERSON:Randi Vita, Sebastian Duesing, Bjoern Peters equivalent electron-microscopy 3D molecular structure determination assay 3D structural organization datum MHC:ligand complex OBI:1110013 ELISPOT assay measuring epitope specific interleukin-2 production by T cells IL-2 release|ELISPOT An enzyme-linked immunospot assay that detects interleukin-2 production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent enzyme-linked immunospot assay ('interleukin-2 production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) OBI:1110037 assay measuring binding of a T cell epitope:MHC:TCR complex T cell binding|any method A T cell epitope assay that measures the binding of T cell receptor to an epitope. IEDB IEDB equivalent assay binding datum MHC:epitope complex binding to TCR OBI:1110059 ELISPOT assay measuring epitope specific interferon-gamma production by T cells IFNg release|ELISPOT An enzyme-linked immunospot assay that detects interferon-gamma production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent enzyme-linked immunospot assay ('interferon-gamma production' and ('process is result of' some 'MHC:epitope complex binding to TCR'))