diff --git a/pyroute2/ndb/schema.py b/pyroute2/ndb/schema.py
index 42a4514cc..4a6692af2 100644
--- a/pyroute2/ndb/schema.py
+++ b/pyroute2/ndb/schema.py
@@ -129,6 +129,7 @@
 
 from pyroute2 import config
 from pyroute2.common import basestring, uuid32
+from pyroute2.netlink import NLM_F_REPLACE
 
 #
 from .objects import address, interface, neighbour, netns, probe, route, rule
@@ -906,6 +907,36 @@ def load_netlink(self, table, target, event, ctable=None, propagate=False):
             compiled = self.compiled[table]
             # a map of sub-NLAs
             nodes = {}
+            # replace
+            r_conditions = []
+            r_values = []
+
+            # Check route replace
+            if (
+                event['header'].get('flags', 0) == NLM_F_REPLACE
+                and event['event'] == 'RTM_NEWROUTE'
+            ):
+                # Replace existing route
+                r_conditions = [table + '.f_target = %s' % self.plch]
+                r_values = [target]
+                for key in self.indices[table]:
+                    if key not in [
+                        'RTA_DST',
+                        'dst_len',
+                        'table',
+                        'RTA_PRIORITY',
+                    ]:
+                        continue
+
+                    r_conditions.append(
+                        table + '.f_%s = %s' % (key, self.plch)
+                    )
+                    value = event.get(key) or event.get_attr(key)
+                    if value is None:
+                        value = self.key_defaults[table][key]
+                    if isinstance(value, (dict, list, tuple, set)):
+                        value = json.dumps(value)
+                    r_values.append(value)
 
             # fetch values (exc. the first two columns)
             for fname, ftype in self.spec[table].items():
@@ -942,6 +973,12 @@ def load_netlink(self, table, target, event, ctable=None, propagate=False):
                 values.append(value)
 
             try:
+                w_fidx = compiled['fidx']
+                w_ivalues = ivalues
+                if r_conditions:
+                    w_fidx = ' AND '.join(r_conditions)
+                    w_ivalues = r_values
+
                 if self.provider == DBProvider.psycopg2:
                     #
                     # run UPSERT -- the DB provider must support it
@@ -957,9 +994,9 @@ def load_netlink(self, table, target, event, ctable=None, propagate=False):
                                 compiled['plchs'],
                                 compiled['knames'],
                                 compiled['fset'],
-                                compiled['fidx'],
+                                w_fidx,
                             ),
-                            (values + values + ivalues),
+                            (values + values + w_ivalues),
                         )
                     )
                     #
@@ -976,8 +1013,8 @@ def load_netlink(self, table, target, event, ctable=None, propagate=False):
                             '''
                                       SELECT count(*) FROM %s WHERE %s
                                       '''
-                            % (table, compiled['fidx']),
-                            ivalues,
+                            % (table, w_fidx),
+                            w_ivalues,
                         ).fetchone()
                     )[0]
                     if count == 0:
@@ -993,8 +1030,8 @@ def load_netlink(self, table, target, event, ctable=None, propagate=False):
                             '''
                                      UPDATE %s SET %s WHERE %s
                                      '''
-                            % (table, compiled['fset'], compiled['fidx']),
-                            (values + ivalues),
+                            % (table, compiled['fset'], w_fidx),
+                            (values + w_ivalues),
                         )
                 else:
                     raise NotImplementedError()