From 0b1be3b529b266713201949da71ce6a0801742ef Mon Sep 17 00:00:00 2001 From: Javad Chamanara Date: Thu, 22 Oct 2020 11:12:01 +0200 Subject: [PATCH] Initial commit --- clarify.ttl | 2063 +++++++++++++++++++++++++++++++++++++++++++++++++++ clarify.txt | 17 + 2 files changed, 2080 insertions(+) create mode 100644 clarify.ttl create mode 100644 clarify.txt diff --git a/clarify.ttl b/clarify.ttl new file mode 100644 index 0000000..983ba47 --- /dev/null +++ b/clarify.ttl @@ -0,0 +1,2063 @@ +@prefix clarify: . +@prefix owl: . +@prefix rdf: . +@prefix rdfs: . +@prefix xsd: . +@prefix dcterms: . +@prefix prv: . + +################################################################################################################################################# +################################################################################################################################################# +################################################################################################################################################# +############################################################### Classes ##################################################################### +################################################################################################################################################# +################################################################################################################################################# +################################################################################################################################################# + +clarify:Concept rdf:type owl:Class; + rdfs:label "Concept"; + rdfs:comment "Constituents of thoughts or real world entities."; + dcterms:modified "2020-09-14"^^xsd:date; + dcterms:creator . + +clarify:Annotation rdf:type owl:Class; + rdfs:label "Annotation"; + rdfs:comment "Annotation of a concept including label, id and source of concept."; + dcterms:modified "2020-09-14"^^xsd:date; + dcterms:creator . + +clarify:Relation rdf:type owl:Class; + rdfs:label "Relation"; + rdfs:comment "Relations between concepts."; + dcterms:modified "2020-09-14"^^xsd:date; + dcterms:creator . + +clarify:CancerPatient rdf:type owl:Class; + rdfs:label "CancerPatient"; + rdfs:comment "Cancer Patient independent of type of their cancer."; + dcterms:modified "2020-09-15"^^xsd:date; + dcterms:creator . + +clarify:SourceName rdf:type owl:Class; + rdfs:label "SourceName"; + rdfs:comment "Represents the provenance of the an annotation."; + dcterms:modified "2020-09-18"^^xsd:date; + dcterms:creator . + +###################################################################################################################################### +######################################################### Drug ################################################################# +###################################################################################################################################### + + +clarify:Drug rdf:type owl:Class; + rdfs:label "Drug"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "A substance used as a medication or in the preparation of medication."; + dcterms:modified "2020-09-14"^^xsd:date; + dcterms:creator . + +clarify:LungCancerDrug rdf:type owl:Class; + rdfs:label "LungCancerDrug"; + rdfs:subClassOf clarify:Drug; + rdfs:comment "A Drug used in the Lung Cancer treatment."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "LCdrugs.ttl"; + dcterms:creator . + +clarify:Biomarker rdf:type owl:Class; + rdfs:label "Biomarker"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "A biomarker, or biological marker is a measurable indicator of some biological state or condition."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "biomarker.ttl"; + prv:File "biomarkerIndication.ttl"; + dcterms:creator . + +clarify:Phenotype rdf:type owl:Class; + rdfs:label "Phenotype"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "The set of observable characteristics of an individual resulting from the interaction of its genotype with the environment. This class include side effects that result from different drugs."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "toxicity.ttl"; + prv:File "drugSideEffectInteraction.ttl"; + dcterms:creator . + +clarify:Target rdf:type owl:Class; + rdfs:label "Target"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "A drug target is a molecule in the body, usually a protein, that is intrinsically associated with a particular disease process and that could be addressed by a drug to produce a desired therapeutic effect."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "target.ttl"; + prv:File "drugTargetInteraction.ttl"; + dcterms:creator . + +clarify:Protein rdf:type owl:Class; + rdfs:label "Protein"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "Large and complex molecules that play many critical roles in the body. They are required for the structure, function and regulation of the body's tissues and organs."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugTargetInteraction.ttl"; + dcterms:creator . + +clarify:Enzyme rdf:type owl:Class; + rdfs:label "Enzyme"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "Macromolecular biological catalyst that accelerate chemical reactions. Most enzymes are proteins."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "enzyme.ttl"; + prv:File "drugEnzymeInteraction.ttl"; + dcterms:creator . + +clarify:Disorder rdf:type owl:Class; + rdfs:label "Disorder"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "A particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not due to any immediate external injury."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "indication_CUI"; + dcterms:creator . + +clarify:DrugDrugInteraction rdf:type owl:Class; + rdfs:label "DrugDrugInteraction"; + rdfs:subClassOf clarify:Relation; + rdfs:comment "The relation between two drugs that interact."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "CRD.ttl"; + prv:File "NCRD.ttl"; + prv:File "drugDrugInteraction_non-symmetric.ttl"; + prv:File "drugDrugInteraction_symmetric.ttl"; + dcterms:creator . + +clarify:DrugDisorderInteraction rdf:type owl:Class; + rdfs:label "DrugDisorderInteraction"; + rdfs:subClassOf clarify:Interaction; + rdfs:comment "A drug-induced disorder."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugDisorder.ttl"; + dcterms:creator . + +clarify:DrugEnzymeInteraction rdf:type owl:Class; + rdfs:label "DrugEnzymeInteraction"; + rdfs:subClassOf clarify:Interaction; + rdfs:comment "Interactions similar to drug receptor interactions where drugs resemble the natural substrates and bind enzymes."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugEnzymeInteraction.ttl"; + dcterms:creator . + +clarify:DrugSideEffectInteraction rdf:type owl:Class; + rdfs:label "DrugSideEffectInteraction"; + rdfs:subClassOf clarify:Relation; + rdfs:comment "Effects of drugs, whether therapeutic or adverse, that are secondary to the one intended."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugSideEffectInteraction.ttl"; + dcterms:creator . + +clarify:DrugTargetInteraction rdf:type owl:Class; + rdfs:label "DrugTargetInteraction"; + rdfs:subClassOf clarify:Interaction; + rdfs:comment "Interactions between chemical compounds and the protein targets in the human body."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugTargetInteraction.ttl"; + dcterms:creator . + +clarify:SymmetricDrugDrugInteraction rdf:type owl:Class; + rdfs:label "SymmetricDrugDrugInteraction"; + rdfs:subClassOf clarify:DrugDrugInteraction; + rdfs:comment "The interactions between two drugs that do not change the effectiveness of the drugs."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugDrugInteraction_symmetric.ttl"; + dcterms:creator . + +clarify:AdverseEvent rdf:type owl:Class; + rdfs:label "AdverseEvent"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "The concept that explains the consequence of the drug drug interaction in their effectiveness."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugDrugInteraction_non-symmetric.ttl"; + prv:File "drugDrugInteraction_symmetric.ttl"; + dcterms:creator . + +clarify:CancerStage rdf:type owl:Class; + rdfs:label "CancerStage"; + rdfs:comment "Represents the assessment of the stage of tumor in a particular date."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "CancerStageIndication.ttl"; + prv:File "stages.ttl"; + dcterms:creator . + +###################################################################################################################################### +##################################################### Publication ############################################################## +###################################################################################################################################### + + +clarify:Publication rdf:type owl:Class; + rdfs:label "Publication"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "Scientific publications."; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "publication_annotation.ttl"; + prv:File "semrep.ttl"; + dcterms:creator . + + +###################################################################################################################################### +##################################################### CLinical Note ############################################################ +###################################################################################################################################### + +clarify:LCPatient rdf:type owl:Class; + rdfs:label "LungCancerPatient"; + rdfs:subClassOf clarify:CancerPatient; + rdfs:comment "A patient who is diagnosed with Lung Cancer."; + dcterms:modified "2020-09-15"^^xsd:date; + dcterms:creator . + +clarify:DrugGroup rdf:type owl:Class; + rdfs:subClassOf clarify:Concept; + rdfs:label "DrugGroup"; + rdfs:comment "The type of drugs that has been prescribed to the patient."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "DrugGroups.ttl"; + dcterms:creator . + +clarify:Gender rdf:type owl:Class; + rdfs:label "Gender"; + rdfs:comment "The gender of patients."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "gender.ttl"; + dcterms:creator . + +clarify:ImmunotherapyDrug rdf:type owl:Class; + rdfs:label "ImmunotherapyDrug"; + rdfs:subClassOf clarify:Drug; + rdfs:comment "An immunotherapy drug which is prescribed as the Lung Cancer treatment."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "immunotherapyList.ttl"; + dcterms:creator . + +clarify:NonOncologicalDrug rdf:type owl:Class; + rdfs:label "NonOncologicalDrug"; + rdfs:subClassOf clarify:Drug; + rdfs:comment "A non-oncological drug which is prescribed to the patient as the treatment of a disorder other than lung cancer."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "nonOncologicalTreatments.ttl"; + dcterms:creator . + +clarify:TkiDrug rdf:type owl:Class; + rdfs:label "TkiDrug"; + rdfs:subClassOf clarify:Drug; + rdfs:comment "Represents TKIs or Tyrosine kinase inhibitors that are type of targeted therapy."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "tkiList.ttl"; + dcterms:creator . + +clarify:OncologicalSurgery rdf:type owl:Class; + rdfs:label "OncologicalSurgery"; + rdfs:subClassOf clarify:Concept; + rdfs:comment " Is the branch of surgery applied to oncology; it focuses on the surgical management of tumors, especially cancerous tumors."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "oncologicalSurgeries.ttl"; + dcterms:creator . + +clarify:TumorType rdf:type owl:Class; + rdfs:subClassOf clarify:Concept; + rdfs:label "TumorType"; + rdfs:comment "The histology kind of the lung cancer. The type of tumor."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:Diagnosis rdf:type owl:Class; + rdfs:label "Diagnosis"; + rdfs:subClassOf clarify:Observation; + rdfs:comment "The identification of the nature of an illness or other problem by examination of the symptoms."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:ToxicityObservation rdf:type owl:Class; + rdfs:label "ToxicityObservation"; + rdfs:subClassOf clarify:Observation; + rdfs:comment "Patient's toxicities on different dates"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_toxicities.ttl"; + dcterms:creator . + +clarify:OncologicalTreatmentLine rdf:type owl:Class; + rdfs:label "OncologicalTreatmentLine"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "Records of patients in clinical notes that are related to oncological treatment lines"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:LiquidBiopsy rdf:type owl:Class; + rdfs:label "LiquidBiopsy"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "A test done on a sample of blood to look for cancer cells from a tumor that are circulating in the blood or for pieces of DNA from tumor cells that are in the blood. It generally provides a picture of all variations found in all tumors, if the cancer has spread."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_biopsy.ttl"; + dcterms:creator . + +clarify:Mutation rdf:type owl:Class; + rdfs:label "Mutation"; + rdfs:subClassOf clarify:Concept; + rdfs:comment "The difference in DNA sequences between individuals within a population. It may occur in germ cells."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_biopsy.ttl"; + dcterms:creator . + +clarify:CancerStageCategory rdf:type owl:Class; + rdfs:label "CancerStageCategory"; + rdfs:comment "Represents the assessment of the stage of tumor in a particular date."; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + + + +################################################################################################################################################# +################################################################################################################################################# +################################################################################################################################################# +######################################################## Properties - attributes ################################################################ +################################################################################################################################################# +################################################################################################################################################# +################################################################################################################################################# + + +clarify:annID rdf:type owl:DatatypeProperty; + rdfs:label "annID"; + rdfs:domain clarify:Annotation; + rdfs:range rdfs:Literal; + rdfs:comment "Identification of instances of Annotation class"; + dcterms:modified "2020-09-14"^^xsd:date; + dcterms:creator . + +clarify:annLabel rdf:type owl:DatatypeProperty; + rdfs:label "annLabel"; + rdfs:domain clarify:Annotation; + rdfs:range rdfs:Literal; + rdfs:comment "Label of instances of Annotation class"; + dcterms:modified "2020-09-14"^^xsd:date; + dcterms:creator . + +clarify:semanticTypeID rdf:type owl:DatatypeProperty; + rdfs:label "semanticTypeID"; + rdfs:domain clarify:Annotation; + rdfs:range rdfs:Literal; + rdfs:comment "The semantic type id provided by UMLS."; + dcterms:modified "2019-01-30"^^xsd:date; + prv:File "CUI_type.ttl"; + dcterms:creator . + +clarify:semanticTypeLabel rdf:type owl:DatatypeProperty; + rdfs:label "semanticTypeLabel"; + rdfs:domain clarify:Annotation; + rdfs:range rdfs:Literal; + rdfs:comment "The semantic type label provided by UMLS."; + dcterms:modified "2020-10-05"^^xsd:date; + prv:File "CUI_type.ttl"; + dcterms:creator . + +clarify:semanticTypeGroup rdf:type owl:DatatypeProperty; + rdfs:label "semanticTypeGroup"; + rdfs:domain clarify:Annotation; + rdfs:range rdfs:Literal; + rdfs:comment "The semantic type group provided by UMLS."; + dcterms:modified "2020-10-05"^^xsd:date; + prv:File "CUI_type.ttl"; + dcterms:creator . + +###################################################################################################################################### +######################################################### Drug ################################################################# +###################################################################################################################################### + +clarify:drugLabel rdf:type owl:DatatypeProperty; + rdfs:label "DrugLabel"; + rdfs:domain clarify:Drug; + rdfs:range rdfs:Literal; + rdfs:comment "Drug label."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drug_DBpedia.ttl"; + dcterms:creator . + +clarify:drugBankID rdf:type owl:DatatypeProperty; + rdfs:label "DrugBankID"; + rdfs:domain clarify:Drug; + rdfs:range rdfs:Literal; + rdfs:comment "Drug Bank ID."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drug_DBpedia.ttl"; + dcterms:creator . + +clarify:biomarkerLabel rdf:type owl:DatatypeProperty; + rdfs:label "biomarkerLabel"; + rdfs:domain clarify:Biomarker; + rdfs:range rdfs:Literal; + rdfs:comment "The name of biomarker."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "Biomarker.ttl"; + dcterms:creator . + +clarify:targetID rdf:type owl:DatatypeProperty; + rdfs:label "targetID"; + rdfs:domain clarify:Target; + rdfs:range rdfs:Literal; + rdfs:comment "Target ID."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugTargetInteraction.ttl"; + dcterms:creator . + +clarify:targetLabel rdf:type owl:DatatypeProperty; + rdfs:label "targetLabel"; + rdfs:domain clarify:Target; + rdfs:range rdfs:Literal; + rdfs:comment "Target Label"; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugTargetInteraction.ttl"; + dcterms:creator . + +clarify:proteinID rdf:type owl:DatatypeProperty; + rdfs:label "proteinID"; + rdfs:domain clarify:Protein; + rdfs:range rdfs:Literal; + rdfs:comment "Uniprot Accession key for protein."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugTargetInteraction.ttl"; + dcterms:creator . + +clarify:proteinLabel rdf:type owl:DatatypeProperty; + rdfs:label "proteinLabel"; + rdfs:domain clarify:Protein; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the name of protein."; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "drugTargetInteraction.ttl"; + dcterms:creator . + +clarify:enzymeID rdf:type owl:DatatypeProperty; + rdfs:label "EnzymeID"; + rdfs:domain clarify:Enzyme; + rdfs:range rdfs:Literal; + rdfs:comment "Enzyme ID."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "enzyme.ttl"; + dcterms:creator . + +clarify:enzymeLabel rdf:type owl:DatatypeProperty; + rdfs:label "EnzymeLabel"; + rdfs:domain clarify:Enzyme; + rdfs:range rdfs:Literal; + rdfs:comment "Enzyme Label."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "enzyme.ttl"; + dcterms:creator . + +clarify:disorderLabel rdf:type owl:DatatypeProperty; + rdfs:label "DisorderLabel"; + rdfs:domain clarify:Disorder; + rdfs:range rdfs:Literal; + rdfs:comment "Disorder Label."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "indication_CUI.ttl"; + dcterms:creator . + +clarify:targetID rdf:type owl:DatatypeProperty; + rdfs:label "targetID"; + rdfs:domain clarify:Target; + rdfs:range rdfs:Literal; + rdfs:comment "Target ID."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "target.ttl"; + dcterms:creator . + +clarify:targetLabel rdf:type owl:DatatypeProperty; + rdfs:label "targetLabel"; + rdfs:domain clarify:Target; + rdfs:range rdfs:Literal; + rdfs:comment "Target Label"; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "target.ttl"; + dcterms:creator . + +clarify:phenotypeLabel rdf:type owl:DatatypeProperty; + rdfs:label "PhenotypeLabel"; + rdfs:domain clarify:Phenotype; + rdfs:range rdfs:Literal; + rdfs:comment "Phenotype Label."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "toxicity.ttl"; + dcterms:creator . + +clarify:toxicityType rdf:type owl:DatatypeProperty; + rdfs:label "toxicityType"; + rdfs:domain clarify:Phenotype; + rdfs:range rdfs:Literal; + rdfs:comment "Toxicity Label."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "toxicity.ttl"; + dcterms:creator . + +clarify:externalLink rdf:type owl:DatatypeProperty; + rdfs:label "externalLink"; + rdfs:domain clarify:Concept; + rdfs:range xsd:anyURI; + rdfs:comment "Link to external resources."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drug_DBpedia.ttl"; + prv:File "enzyme.ttl"; + dcterms:creator . + +clarify:uniprotID rdf:type owl:DatatypeProperty; + rdfs:label "uniprotID"; + rdfs:domain clarify:Concept; + rdfs:range rdfs:Literal; + rdfs:comment "External relationship to accession ID in uniprot."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "enzyme.ttl"; + prv:File "target.ttl"; + dcterms:creator . + +clarify:dse_AvgFrequency rdf:type owl:DatatypeProperty; + rdfs:label "dse_AvgFrequency"; + rdfs:domain clarify:DrugSideEffectInteraction; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the average frequecy of particular drug having specific side effect."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugSideEffectInteraction.ttl"; + dcterms:creator . + +clarify:impact rdf:type owl:DatatypeProperty; + rdfs:label "impact"; + rdfs:domain clarify:AdverseEvent; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the type impact of the adverse event i.e. increase/decrease"; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugDrugInteraction_non-symmetric.ttl"; + prv:File "drugDrugInteraction_symmetric.ttl"; + dcterms:creator . + +###################################################################################################################################### +####################################################### Publication ############################################################# +###################################################################################################################################### + +clarify:pubmedID rdf:type owl:DatatypeProperty; + rdfs:label "PubMed ID"; + rdfs:domain clarify:Publication; + rdfs:range rdfs:Literal; + rdfs:comment "PubMed ID."; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "publication_annotation.ttl"; + dcterms:creator . + +clarify:confidence rdf:type owl:DatatypeProperty; + rdfs:label "confidence"; + rdfs:domain clarify:Relation; + rdfs:range rdfs:Literal; + rdfs:comment "Confidence score of the concept"; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "semrep.ttl"; + dcterms:creator . + +clarify:semanticType rdf:type owl:DatatypeProperty; + rdfs:label "semanticType"; + rdfs:domain clarify:Annotation; + rdfs:range rdfs:Literal; + rdfs:comment "A list with the allowed semantic_types for this Annotation in the UMLS. "; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "publication_annotation.ttl"; + dcterms:creator . + +###################################################################################################################################### +###################################################### Clinical Note ########################################################### +###################################################################################################################################### + +clarify:annLabel_SPA rdf:type owl:DatatypeProperty; + rdfs:label "annLabel_SPA"; + rdfs:domain clarify:Annotation; + rdfs:range rdfs:Literal; + rdfs:comment "Spanish label of instances of Annotation class"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "chemotherapyList.ttl"; + prv:File "comorbidities.ttl"; + prv:File "immunotherapyList.ttl"; + prv:File "nonOncologicalTreatments.ttl"; + prv:File "tkiList.ttl"; + prv:File "toxicities.ttl"; + dcterms:creator . + +clarify:drugLabel_ENG rdf:type owl:DatatypeProperty; + rdfs:label "drugLabel_ENG"; + rdfs:domain clarify:Drug; + rdfs:range rdfs:Literal; + rdfs:comment "Drug label."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "chemotherapyList.ttl"; + prv:File "immunotherapyList.ttl"; + prv:File "nonOncologicalTreatments.ttl"; + prv:File "tkiList.ttl"; + dcterms:creator . + +clarify:disorderLabel_ENG rdf:type owl:DatatypeProperty; + rdfs:label "disorderLabel_ENG"; + rdfs:domain clarify:Disorder; + rdfs:range rdfs:Literal; + rdfs:comment "Disorder label."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "comorbidities.ttl"; + dcterms:creator . + +clarify:drugGroupLabel rdf:type owl:DatatypeProperty; + rdfs:label "drugGroupLabel"; + rdfs:domain clarify:DrugGroup; + rdfs:range rdfs:Literal; + rdfs:comment "Drug Group Label."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "drugGroups.ttl"; + dcterms:creator . + +clarify:genderLabel_ENG rdf:type owl:DatatypeProperty; + rdfs:label "genderLabel_ENG"; + rdfs:domain clarify:Gender; + rdfs:range rdfs:Literal; + rdfs:comment "Gender name (Female/Male/F/M)"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "gender.ttl"; + dcterms:creator . + +clarify:oncologicalSurgeryLabel_ENG rdf:type owl:DatatypeProperty; + rdfs:label "oncologicalSurgeryLabel_ENG"; + rdfs:domain clarify:OncologicalSurgery; + rdfs:range rdfs:Literal; + rdfs:comment "Name of oncological surgery "; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "oncologicalSurgeries.ttl"; + dcterms:creator . + +clarify:CancerStageLabel rdf:type owl:DatatypeProperty; + rdfs:label "CancerStageLabel"; + rdfs:domain clarify:CancerStage; + rdfs:range rdfs:Literal; + rdfs:comment "Label of Tumor Stage"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "stages.ttl"; + dcterms:creator . + +clarify:toxicityLabel_ENG rdf:type owl:DatatypeProperty; + rdfs:label "toxicityLabel_ENG"; + rdfs:domain clarify:Phenotype; + rdfs:range rdfs:Literal; + rdfs:comment "Label of Toxicity"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "toxicities.ttl"; + dcterms:creator . + +clarify:beingIn_hospitalHealthArea rdf:type owl:DatatypeProperty; + rdfs:label "beingIn_hospitalHealthArea"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "if the patient lives in a city which belong to the municipal scope area awarded to the hospital (True/False)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:distanceToHospital rdf:type owl:DatatypeProperty; + rdfs:label "distanceToHospital"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "The distance in kilometers from the city in which the patient lives to the hospital."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:radonRiskLevel rdf:type owl:DatatypeProperty; + rdfs:label "radonRiskLevel"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "The radon risk level [from 1 (lowest) to 6 (highest)].."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfCigarettesPerYear rdf:type owl:DatatypeProperty; + rdfs:label "numberOfCigarettesPerYear"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "The number of cigarettes per year if the patient is current or former smoker."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:isDead rdf:type owl:DatatypeProperty; + rdfs:label "isDead"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "If the patient is currently dead (True/False)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:ageAtDeath rdf:type owl:DatatypeProperty; + rdfs:label "ageAtDeath"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "The age at which the patient died."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:placeOfDeath rdf:type owl:DatatypeProperty; + rdfs:label "placeOfDeath"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "The place where the patient died (home/ hospital/ alive: if the patient is alive)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:smoking rdf:type owl:DatatypeProperty; + rdfs:label "smoking"; + rdfs:domain clarify:CancerPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Whether the patient smokes or not; smoker or no_smoker."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_biomarker rdf:type owl:DatatypeProperty; + rdfs:label "biomarkers"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "If an Entity has been studied, and if the result has been positive or negative in any biomarker (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_chemotherapy rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_chemotherapy"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Whether the patient has received chemotherapy oncology treatment (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_tki rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_tki"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Whether the patient has received tki oncology treatment (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_immunotherapy rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_immunotherapy"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Whether the patient has received immunotherapy oncology treatment (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_antiangiogenic rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_antiangiogenic"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Whether the patient has received angiogenesis inhibitor treatment (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_radiationtherapy rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_radiationtherapy"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Whether the patient has received radiationtherapy oncology treatment (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_surgery rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_surgery"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Whether the patient has received radiationtherapy oncology treatment (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_brainMetastasis rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_brainMetastasis"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Whether brain metastasis has been detected in the patient (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalMonths rdf:type owl:DatatypeProperty; + rdfs:label "survivalMonths"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Months from diagnosis to death or until the last documented record of the patient."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:patientCurrentStatus rdf:type owl:DatatypeProperty; + rdfs:label "patientCurrentStatus"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Current status of Lung Cancer patient (dead, alive_with_cancer, alive_without_cancer, withdrawn of the study)"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDiagnosisCancerStage rdf:type owl:ObjectProperty; + rdfs:label "hasDiagnosisCancerStage"; + rdfs:domain clarify:Diagnosis; + rdfs:range clarify:CancerStage; + rdfs:comment "The tumor stage at the time of the diagnosis."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDiagnosisCancerStageCategory rdf:type owl:ObjectProperty; + rdfs:label "hasDiagnosisCancerStage"; + rdfs:domain clarify:Diagnosis; + rdfs:range clarify:CancerStageCategory; + rdfs:comment "The tumor stage type at the time of the diagnosis (Early/Intermediate/Advanced)."; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDiagnosisTumorType rdf:type owl:ObjectProperty; + rdfs:label "hasDiagnosisTumorType"; + rdfs:domain clarify:Diagnosis; + rdfs:range clarify:TumorType; + rdfs:comment "Tumor Type at diagnosis"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDiagnosisAge rdf:type owl:DatatypeProperty; + rdfs:label "hasDiagnosisAge"; + rdfs:domain clarify:Diagnosis; + rdfs:range rdfs:Literal; + rdfs:comment "The age of the patient at diagnosis of the disease."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDate rdf:type owl:DatatypeProperty; + rdfs:label "hasDate"; + rdfs:domain clarify:Concept; + rdfs:range rdfs:Literal; + rdfs:comment "Related date."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_toxicities.ttl"; + dcterms:creator . + +clarify:treatmentType rdf:type owl:DatatypeProperty; + rdfs:label "treatmentType"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Type of oncological treatment"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:treatmentLineNumber rdf:type owl:DatatypeProperty; + rdfs:label "treatmentLineNumber"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Number of oncological treatment line"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:treatmentInitDate rdf:type owl:DatatypeProperty; + rdfs:label "treatmentInitDate"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Start date of the oncological treatment line"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:treatmentFinishDate rdf:type owl:DatatypeProperty; + rdfs:label "treatmentFinishDate"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Finish date of the oncological treatment line"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:treatmentDurationMonths rdf:type owl:DatatypeProperty; + rdfs:label "treatmentDurationMonths"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Months of treatment duration."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_toxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_toxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed any type of toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_generalToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_generalToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed general toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_gastrointestinalToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_gastrointestinalToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed gastrointestinal toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + + +clarify:existenceOf_endocrinaToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_endocrinaToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed endocrina toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_cutaneaToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_cutaneaToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed cutanea toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_pneumologicalToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_pneumologicalToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed pneumological toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_analyticalToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_analyticalToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed analytical toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_neurologicalToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_neurologicalToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed neurological toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_astheniaToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_astheniaToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed asthenia toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_allergyToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_allergyToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed allergic toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_liverToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_liverToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed liver analysis toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_kidneyToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_kidneyToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed kidney toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_otolaryngologyToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_otolaryngologyToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed otolaryngology toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_cardiologicalToxicity rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_cardiologicalToxicity"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has developed cardiological toxicities during a specific line of treatment (yes/no)."; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:existenceOf_brainMetastasis_inOncologicalTreatmentLine rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_brainMetastasis_inOncologicalTreatmentLine"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range rdfs:Literal; + rdfs:comment "Existence of brain metastasis in oncological treatment line (yes/no)"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:sampleDate rdf:type owl:DatatypeProperty; + rdfs:label "sampleDate"; + rdfs:domain clarify:Test; + rdfs:range rdfs:Literal; + rdfs:comment "Date on which the biopsy sample has been taken."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_biopsy.ttl"; + dcterms:creator . + +clarify:resultDate rdf:type owl:DatatypeProperty; + rdfs:label "resultDate"; + rdfs:domain clarify:LiquidBiopsy; + rdfs:range rdfs:Literal; + rdfs:comment "Date on which the biopsy result has been provided."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_biopsy.ttl"; + dcterms:creator . + +clarify:targetTotal rdf:type owl:DatatypeProperty; + rdfs:label "targetTotal"; + rdfs:domain clarify:LiquidBiopsy; + rdfs:range rdfs:Literal; + rdfs:comment "The percentage of circulating tumor DNA in the blood"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_biopsy.ttl"; + dcterms:creator . + +clarify:copiesMicroliterFam rdf:type owl:DatatypeProperty; + rdfs:label "copiesMicroliterFam"; + rdfs:domain clarify:LiquidBiopsy; + rdfs:range rdfs:Literal; + rdfs:comment "Number of mutated copies per microliter of blood"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_biopsy.ttl"; + dcterms:creator . + +clarify:copiesMicroliterVic rdf:type owl:DatatypeProperty; + rdfs:label "copiesMicroliterVic"; + rdfs:domain clarify:LiquidBiopsy; + rdfs:range rdfs:Literal; + rdfs:comment "Number of non-mutated copies per microliter of blood"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_biopsy.ttl"; + dcterms:creator . + +clarify:existenceOf_systemicPrognosis rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_systemicPrognosis"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient has progressed to an advanced stage.(True/ False)"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_palliativeCare_closeToDeath rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_palliativeCare_closeToDeath"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient received palliative care in his/her dying month.(True/ False)"; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_palliativeCare_BeforeDeath rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_palliativeCare_BeforeDeath"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient received palliative care a month before his/her death.(True/ False)"; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_deathInHospital_rightAfterTreatment rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_deathInHospital_rightAfterTreatment"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates if the patient died in the hospital the month after receiving his/her treatment.(True/ False)"; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDiagnosisAgeCategory_over70 rdf:type owl:DatatypeProperty; + rdfs:label "hasDiagnosisAgeCategory_over70"; + rdfs:domain clarify:Diagnosis; + rdfs:range rdfs:Literal; + rdfs:comment "Represnets the age group that the lung cancer patient belongs to at the time of the diagnostic (<70, >=70)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDiagnosisAgeCategory rdf:type owl:DatatypeProperty; + rdfs:label "hasDiagnosisAgeCategory"; + rdfs:domain clarify:Diagnosis; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the lung cancer patient's age range at the time of diagnosis diagnosed (40 <, 40-50, 50-60, 60-70, 70 >)."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_deathInHospital_rightAfterTreatment rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_deathInHospital_rightAfterTreatment"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the lung cancer patient died in the hospital the month after receiving his/her treatment (yes, no)."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_antiangiogentic rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_antiangiogentic"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the patient was treated with antiangiogenic therapy."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:firstDocumentDate rdf:type owl:DatatypeProperty; + rdfs:label "firstDocumentDate"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:ageCategoryAtDeath_over70 rdf:type owl:DatatypeProperty; + rdfs:label "ageCategoryAtDeath_over70"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the age group that the lung cancer patient belongs to at the time of death (<70, >=70)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:startAge rdf:type owl:DatatypeProperty; + rdfs:label "startAge"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the age of the lung cancer patient at the time of diagnosis."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:comorbidities_beforedx_jkes rdf:type owl:DatatypeProperty; + rdfs:label "comorbidities_beforedx_jkes"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfMonth_afterDiagnosis_beforeResistMutation rdf:type owl:DatatypeProperty; + rdfs:label "numberOfMonth_afterDiagnosis_beforeResistMutation"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the elapsed time in months, from diagnosis to detection of resist (if negative the difference, resist was detected before the diagnosis, otherwise it was detected after)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:isParticipatedIn_clinicalTrial rdf:type owl:DatatypeProperty; + rdfs:label "isParticipatedIn_clinicalTrial"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the lung cancer patient partipated in any clinical trial."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_stageIVprogression rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_stageIVprogression"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the lung cancer patient has progressed to an advanced stage."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:categorizedNumberOfDrugs_beforeDiagnosis rdf:type owl:DatatypeProperty; + rdfs:label "categorizedNumberOfDrugs_beforeDiagnosis"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Categorical number of drugs prescribed to the lung cancer patient before diagnosis (0, 1-2,3-4,>5)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfMOnths_afterSensitMutation_beforeResistMutation rdf:type owl:DatatypeProperty; + rdfs:label "numberOfMOnths_afterSensitMutation_beforeResistMutation"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the elapsed time in months, from detection of sensit mutation to detection of resist (if negative the difference, resist was detected before sensit, otherwise it was detected after)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasCardioVascularRiskFactor rdf:type owl:DatatypeProperty; + rdfs:label "hasCardioVascularRiskFactor"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the lung cancer patient had cardiovascular risk factors previous to the diagnosis."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:lastCancerStageCategory rdf:type owl:DatatypeProperty; + rdfs:label "lastCancerStageCategory"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the last known stage of the lung cancer patient (Early, Intermediate, Advanced)."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalDays_afterFirstTreatmentLine rdf:type owl:DatatypeProperty; + rdfs:label "survivalDays_afterFirstTreatmentLine"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the number of survival days since the patient received his/her 1st treatment line."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalDays_afterProgression rdf:type owl:DatatypeProperty; + rdfs:label "survivalDays_afterProgression"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the number of survival days since the patient progressed to an advanced stage."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfDays_afterDiagnosis_beforeResistMutation rdf:type owl:DatatypeProperty; + rdfs:label "numberOfDays_afterDiagnosis_beforeResistMutation"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the elapsed time in days, from diagnosis to detection of resist mutation (if negative the difference, the mutation was detected before diagnosis, otherwise it was detected after)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfToxicities_after2018 rdf:type owl:DatatypeProperty; + rdfs:label "numberOfToxicities_after2018"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the number of patient’s toxicities after 2018."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalDays rdf:type owl:DatatypeProperty; + rdfs:label "survivalDays"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the patient's survival days, from diagnosis to date of death if the patient is dead or date file reception in other case."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfToxicities_before2018 rdf:type owl:DatatypeProperty; + rdfs:label "numberOfToxicities_before2018"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the number of patient’s toxicities before 2018."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:resist_mutation_date rdf:type owl:DatatypeProperty; + rdfs:label "resist_mutation_date"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the date when resist mutation was detected."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfComorbidities_beforedx_jkes rdf:type owl:DatatypeProperty; + rdfs:label "numberOfComorbidities_beforedx_jkes"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfDays_afterSensitMutation_beforeResistMutation rdf:type owl:DatatypeProperty; + rdfs:label "numberOfDays_afterSensitMutation_beforeResistMutation"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the elapsed time in days, from detection of sensit mutation to detection of resist (if negative the difference, resist was detected before sensit, otherwise it was detected after)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_palliativeCare_closeToDeath rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_palliativeCare_closeToDeath"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the patient received palliative care in his/her dying month (yes, no)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalMonths_afterSecondTreatmentLine rdf:type owl:DatatypeProperty; + rdfs:label "survivalMonths_afterSecondTreatmentLine"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the number of survival months since the patient received his/her 2nd treatment line."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:firstNoteDate rdf:type owl:DatatypeProperty; + rdfs:label "firstNoteDate"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalDays_afterSecondTreatmentLine rdf:type owl:DatatypeProperty; + rdfs:label "survivalDays_afterSecondTreatmentLine"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalDays_afterThirdTreatmentLine rdf:type owl:DatatypeProperty; + rdfs:label "survivalDays_afterThirdTreatmentLine"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:Mutated_Sensit rdf:type owl:DatatypeProperty; + rdfs:label "Mutated_Sensit"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the patient has tested positive for the sensit mutation."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfToxicities rdf:type owl:DatatypeProperty; + rdfs:label "numberOfToxicities"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the number of patient’s toxicities."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalMonths_afterFirstTreatmentLine rdf:type owl:DatatypeProperty; + rdfs:label "survivalMonths_afterFirstTreatmentLine"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the number of survival months since the patient received his/her 1st treatment line."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_overTreatment rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_overTreatment"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the patient received oncological treatment instead palliative care in his/her last living month (yes, no)."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:manualDiagnosisDate rdf:type owl:DatatypeProperty; + rdfs:label "manualDiagnosisDate"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:deathDate rdf:type owl:DatatypeProperty; + rdfs:label "deathDate"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the lung cancer patient's date of death (structured information provided by HUPHM)."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOf_targetedTherapy_treatmentLines rdf:type owl:DatatypeProperty; + rdfs:label "numberOf_targetedTherapy_treatmentLines"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the total number of TKI treatment lines carried out (except radiotherapy and surgery)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:Mutated_Resist rdf:type owl:DatatypeProperty; + rdfs:label "Mutated_Resist"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the patient has tested positive for the resist mutation."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:categorizedNumberOfToxicities rdf:type owl:DatatypeProperty; + rdfs:label "categorizedNumberOfToxicities"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the categorical number of patient’s toxicities (0, 1-2,3-4, 5-10, >10)."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:firstReportDate rdf:type owl:DatatypeProperty; + rdfs:label "firstReportDate"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOf_chemotherapy_treatmentLines rdf:type owl:DatatypeProperty; + rdfs:label "numberOf_chemotherapy_treatmentLines"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the total number of QT treatment lines carried out (except radiotherapy and surgery)"; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfDays_afterDiagnosis_beforeSensitMutation rdf:type owl:DatatypeProperty; + rdfs:label "numberOfDays_afterDiagnosis_beforeSensitMutation"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "INdicates the elapsed time in days, from diagnosis to detection of sensit mutation (if negative the difference, the mutation was detected before diagnosis, otherwise it was detected after)."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOf_oncological_treatmentLines rdf:type owl:DatatypeProperty; + rdfs:label "numberOf_oncological_treatmentLines"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the total number of oncology treatment lines carried out (except radiotherapy and surgery)."; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:lastDocumentDate rdf:type owl:DatatypeProperty; + rdfs:label "lastDocumentDate"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-21"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_palliativeCare_BeforeDeath rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_palliativeCare_BeforeDeath"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the patient received palliative care a month before his/her death (yes, no)."; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:sensit_mutation_date rdf:type owl:DatatypeProperty; + rdfs:label "sensit_mutation_date"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the date of sensit mutation detection."; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOf_antiangiogenic_treatmentLines rdf:type owl:DatatypeProperty; + rdfs:label "numberOf_antiangiogenic_treatmentLines"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the total number of antiangiogenic treatment lines carried out (except radiotherapy and surgery)."; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:ageCategoryAtDeath rdf:type owl:DatatypeProperty; + rdfs:label "ageCategoryAtDeath"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "INdicates the lung cancer patient's age range when he/she died (40 <, 40-50, 50-60, 60-70, 70 >)"; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:commonCauseOfDeath rdf:type owl:DatatypeProperty; + rdfs:label "commonCauseOfDeath"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the lung cancer patient's cause of death if it is among the most common causes of death"; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfNotes rdf:type owl:DatatypeProperty; + rdfs:label "numberOfNotes"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalTime_MoreOrLessThan12months rdf:type owl:DatatypeProperty; + rdfs:label "survivalTime_MoreOrLessThan12months"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the survival categories (<=12m, >12m)"; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOf_immunotherapy_treatmentLines rdf:type owl:DatatypeProperty; + rdfs:label "numberOf_immunotherapy_treatmentLines"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the total number of immunotherapy treatment lines carried out (except radiotherapy and surgery)"; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:treatmentsOrder rdf:type owl:DatatypeProperty; + rdfs:label "treatmentsOrder"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Provides a sequence of characters with the types of treatments that have been followed separated by '|' and put in the order in which they were prescribed"; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:survivalMonths_afterThirdTreatmentLine rdf:type owl:DatatypeProperty; + rdfs:label "survivalMonths_afterThirdTreatmentLine"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the number of survival months since the patient received his/her 3rd treatment line"; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:city rdf:type owl:DatatypeProperty; + rdfs:label "city "; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Represents the city of residence of the patient (structured information provided by HUPHM)"; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfReports rdf:type owl:DatatypeProperty; + rdfs:label "numberOfReports"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfMonths_afterDiagnosis_beforeSensitMutation rdf:type owl:DatatypeProperty; + rdfs:label "numberOfMonths_afterDiagnosis_beforeSensitMutation"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the elapsed time in months, from diagnosis to detection of sensit (if negative the difference, sensit was detected before the diagnosis, otherwise it was detected after)."; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:existenceOf_familyHistory rdf:type owl:DatatypeProperty; + rdfs:label "existenceOf_familyHistory"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates that if the patient has familial history"; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:stageIVDate rdf:type owl:DatatypeProperty; + rdfs:label "stageIVDate"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "Indicates the date when the patient was diagnosed with stage IV."; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:monthsInTheSystem rdf:type owl:DatatypeProperty; + rdfs:label "monthsInTheSystem"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment ""; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:numberOfDrugs_beforeDiagnosis rdf:type owl:DatatypeProperty; + rdfs:label "numberOfDrugs_beforeDiagnosis"; + rdfs:domain clarify:LCPatient; + rdfs:range rdfs:Literal; + rdfs:comment "INdicates the number of drugs used by the patient before diagnosis"; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + + +################################################################################################################################################# +################################################################################################################################################# +################################################################################################################################################# +#################################################### Properties - relationships ################################################################# +################################################################################################################################################# +################################################################################################################################################# +################################################################################################################################################# + +clarify:provenance rdf:type owl:ObjectProperty; + rdfs:label "provenance"; + rdfs:domain clarify:Concept; + rdfs:range clarify:SourceName; + rdfs:comment "The name of the source from which the concept is extracted or derived"; + dcterms:modified "2020-09-18"^^xsd:date; + dcterms:creator . + +clarify:hasCUIAnnotation rdf:type owl:ObjectProperty; + rdfs:label "hasCUIAnnotation"; + rdfs:domain clarify:Concept; + rdfs:range clarify:Annotation; + rdfs:comment "CUI annotation of the concept."; + dcterms:modified "2020-09-14"^^xsd:date; + dcterms:creator . + + +###################################################################################################################################### +######################################################### Drug ################################################################# +###################################################################################################################################### + +clarify:biomarker_has_indication rdf:type owl:ObjectProperty; + rdfs:label "biomarker_has_indication"; + rdfs:domain clarify:Biomarker; + rdfs:range clarify:Drug; + rdfs:comment "A biomarker has indication Drug"; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "biomarkerIndication.ttl"; + dcterms:creator . + +clarify:interactor1 rdf:type owl:ObjectProperty; + rdfs:label "interactor1"; + rdfs:domain clarify:Interaction; + rdfs:range clarify:Drug; + rdfs:comment "Interactor 1"; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugDisorder.ttl"; + dcterms:creator . + +clarify:interactor2 rdf:type owl:ObjectProperty; + rdfs:label "interactor2"; + rdfs:domain clarify:Interaction; + rdfs:range clarify:Concept; + rdfs:comment "Interactor 2"; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugDisorder.ttl"; + dcterms:creator . + +clarify:drug_isRelatedTo_dse rdf:type owl:ObjectProperty; + rdfs:label "drug_isRelatedTo_dse"; + rdfs:domain clarify:Drug; + rdfs:range clarify:DrugSideEffect; + rdfs:comment "relationship between drug and drug-sideEffect relation."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugSideEffectInteraction.ttl"; + prv:File "drugToxicityInteraction.ttl"; + dcterms:creator . + +clarify:sideEffect_isRelatedTo_dse rdf:type owl:ObjectProperty; + rdfs:label "sideEffect_isRelatedTo_dse"; + rdfs:domain clarify:Phenotype; + rdfs:range clarify:DrugSideEffect; + rdfs:comment "relationship between sideEffect and drug-sideEffect relation."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugSideEffectInteraction.ttl"; + prv:File "drugToxicityInteraction.ttl"; + dcterms:creator . + +clarify:enzyme_isRelatedTo_gene rdf:type owl:ObjectProperty; + rdfs:label "enzyme_isRelatedTo_gene"; + rdfs:domain clarify:Enzyme; + rdfs:range clarify:Gene; + rdfs:comment "The relationship between the enzyme and the gene from which it is produced."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "enzyme.ttl"; + dcterms:creator . + +clarify:affects rdf:type owl:ObjectProperty; + rdfs:label "affects"; + rdfs:domain clarify:DrugDrugInteraction; + rdfs:range clarify:Drug; + rdfs:comment "The conncetion between drug that affects by the other one through their interaction and the interaction node."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "CRD.ttl"; + prv:File "NCRD.ttl"; + dcterms:creator . + +clarify:isAffected rdf:type owl:ObjectProperty; + rdfs:label "isAffected"; + rdfs:domain clarify:DrugDrugInteraction; + rdfs:range clarify:Drug; + rdfs:comment "The conncetion between drug that is affected by the other one through their interaction and the interaction node."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "CRD.ttl"; + prv:File "NCRD.ttl"; + dcterms:creator . + +clarify:precipitant_drug rdf:type owl:ObjectProperty; + rdfs:label "precipitant_drug"; + rdfs:domain clarify:DrugDrugInteraction; + rdfs:range clarify:Drug; + rdfs:comment "The relationship between the drug drug interaction and corresponding precipitant drug."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugDrugInteraction_non-symmetric.ttl"; + prv:File "drugDrugInteraction_symmetric.ttl"; + dcterms:creator . + +clarify:object_drug rdf:type owl:ObjectProperty; + rdfs:label "object_drug"; + rdfs:domain clarify:DrugDrugInteraction; + rdfs:range clarify:Drug; + rdfs:comment "The relationship between the drug drug interaction and corresponding object drug."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugDrugInteraction_non-symmetric.ttl"; + prv:File "drugDrugInteraction_symmetric.ttl"; + dcterms:creator . + +clarify:effect rdf:type owl:ObjectProperty; + rdfs:label "effect"; + rdfs:domain clarify:DrugDrugInteraction; + rdfs:range clarify:AdverseEvent; + rdfs:comment "The relationship between the drug drug interaction and corresponding adverse event."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "drugDrugInteraction_non-symmetric.ttl"; + prv:File "drugDrugInteraction_symmetric.ttl"; + dcterms:creator . + +clarify:target_isRelatedTo_gene rdf:type owl:ObjectProperty; + rdfs:label "target_isRelatedTo_gene"; + rdfs:domain clarify:Target; + rdfs:range clarify:Gene; + rdfs:comment "The relationship between the target and the gene from which it is produced."; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "target.ttl"; + dcterms:creator . + +clarify:CancerStage_has_indication rdf:type owl:ObjectProperty; + rdfs:label "CancerStage_has_indication"; + rdfs:domain clarify:CancerStage; + rdfs:range clarify:Drug; + rdfs:comment "Tumor stage has indication drug"; + dcterms:modified "2020-09-14"^^xsd:date; + prv:File "CancerStageIndication.ttl"; + dcterms:creator . + +clarify:hasHPOAnnotation rdf:type owl:ObjectProperty; + rdfs:label "hasHPOAnnotation"; + rdfs:domain clarify:Phenotype; + rdfs:range clarify:Annotation; + rdfs:comment "HPO annotation of the phenotype."; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "toxicity.ttl"; + dcterms:creator . + +###################################################################################################################################### +##################################################### Publication ############################################################## +###################################################################################################################################### + +clarify:hasAnnotation rdf:type owl:ObjectProperty; + rdfs:label "hasAnnotation"; + rdfs:domain clarify:Relation; + rdfs:range clarify:Annotation; + rdfs:comment "Connection between the annotation and the relation between annotation and publication"; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "publication_annotation.ttl"; + dcterms:creator . + +clarify:annotates rdf:type owl:ObjectProperty; + rdfs:label "annotates"; + rdfs:domain clarify:Relation; + rdfs:range clarify:Publication; + rdfs:comment "Connection between mentionedIn or HasTopic relation with CUI."; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "publication_annotation.ttl"; + dcterms:creator . + +clarify:relation_isRelatedTo_annotation rdf:type owl:ObjectProperty; + rdfs:label "relation_isRelatedTo_annotation"; + rdfs:domain clarify:Relation; + rdfs:range clarify:Annotation; + rdfs:comment "The relationship between the relation and the annotation."; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "publication_annotation.ttl"; + dcterms:creator . + +clarify:relation_isRelatedTo_publication rdf:type owl:ObjectProperty; + rdfs:label "relation_isRelatedTo_publication"; + rdfs:domain clarify:Relation; + rdfs:range clarify:Publication; + rdfs:comment "The relationship between the relation and the publication."; + dcterms:modified "2020-09-23"^^xsd:date; + prv:File "publication_annotation.ttl"; + dcterms:creator . + +###################################################################################################################################### +##################################################### Clinical Note ############################################################ +###################################################################################################################################### + +clarify:gender rdf:type owl:ObjectProperty; + rdfs:label "gender"; + rdfs:domain clarify:CancerPatient; + rdfs:range clarify:Gender; + rdfs:comment "Gender value of the patient."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDiagnosis rdf:type owl:ObjectProperty; + rdfs:label "hasDiagnosis"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Diagnosis; + rdfs:comment "Patient's initial diagnosis."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDiagnosisDate rdf:type owl:ObjectProperty; + rdfs:label "hasDiagnosisDate"; + rdfs:domain clarify:Diagnosis; + rdfs:range clarify:Date; + rdfs:comment "Diagnosis date of the disease."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasDiagnosisPerformanceStatus rdf:type owl:ObjectProperty; + rdfs:label "hasDiagnosisPerformanceStatus"; + rdfs:domain clarify:Diagnosis; + rdfs:range clarify:PerformanceStatus; + rdfs:comment "The Performance Status of the patient at diagnosis."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasToxicity rdf:type owl:ObjectProperty; + rdfs:label "hasToxicity"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Phenotype; + rdfs:comment "Toxicity in a specific date"; + dcterms:modified "2020-09-18"^^xsd:date; + prv:File "patient_toxicities.ttl"; + dcterms:creator . + +clarify:hasTki rdf:type owl:ObjectProperty; + rdfs:label "hasTki"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Drug; + rdfs:comment "Connection between patient with lung cancer and the tki drugs that has been prescribed."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_tkiList.ttl"; + dcterms:creator . + +clarify:treatment_has_drug rdf:type owl:ObjectProperty; + rdfs:label "treatment_has_drug"; + rdfs:domain clarify:OncologicalTreatmentLine; + rdfs:range clarify:Drug; + rdfs:comment "A oncological treatment line has drugs"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine_drugs.ttl"; + dcterms:creator . + +clarify:hasOncologicalTreatmentLine rdf:type owl:ObjectProperty; + rdfs:label "hasOncologicalTreatmentLine"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:OncologicalTreatmentLine; + rdfs:comment "Oncological treatment line received by the patient."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalTreatmentLine.ttl"; + dcterms:creator . + +clarify:hasOncologicalSurgery rdf:type owl:ObjectProperty; + rdfs:label "hasOncologicalSurgery"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:OncologicalSurgery; + rdfs:comment "A relation between each oncological surgery observation and related data."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_oncologicalSurgeries.ttl"; + dcterms:creator . + +clarify:hasNonOncologicalDrug rdf:type owl:ObjectProperty; + rdfs:label "hasNonOncologicalDrug"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Drug; + rdfs:comment "The patient has non-oncological drug"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_nonOncologycalTreatments.ttl"; + dcterms:creator . + +clarify:hasImmunotherapy rdf:type owl:ObjectProperty; + rdfs:label "hasImmunotherapy"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Drug; + rdfs:comment "Connection between patient with lung cancer and the immunotherapy drugs that has been prescribed."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_ImmunotherapyList.ttl"; + dcterms:creator . + +clarify:hasDrugGroup rdf:type owl:ObjectProperty; + rdfs:label "hasDrug"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:DrugGroup; + rdfs:comment "Connection between patient with lung cancer and the types of drugs that has been prescribed."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_drugGroups.ttl"; + dcterms:creator . + +clarify:hasComorbidity rdf:type owl:ObjectProperty; + rdfs:label "hasComorbidity"; + rdfs:domain clarify:CancerPatient; + rdfs:range clarify:Disorder; + rdfs:comment "Connection between patient with lung cancer or Alzheimer and her/his Comorbidities."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_comorbidities.ttl"; + dcterms:creator . + +clarify:hasChemotherapy rdf:type owl:ObjectProperty; + rdfs:label "hasChemotherapy"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Drug; + rdfs:comment "Connection between patient with lung cancer and the Chemotherapy drugs that has been prescribed."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_chemotherapyList.ttl"; + dcterms:creator . + +clarify:hasLiquidBiopsy rdf:type owl:ObjectProperty; + rdfs:label "hasLiquidBiopsy"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:LiquidBiopsy; + rdfs:comment "Connection between patient with lung cancer and the liquid biopsy tests that has been run."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_biopsy.ttl"; + dcterms:creator . + +clarify:hasMutation rdf:type owl:ObjectProperty; + rdfs:label "hasMutation"; + rdfs:domain clarify:LiquidBiopsy; + rdfs:range clarify:Mutation; + rdfs:comment "The Liquid biopsy has a mutation"; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient_biopsy.ttl"; + dcterms:creator . + +clarify:existenceOf_bioEgfr rdf:type owl:ObjectProperty; + rdfs:label "existenceOf_bioEgfr"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Biomarker; + rdfs:comment "Whether the patient's biopsies have been studied in terms of EGFR biomarker and if the result has been positive or negative in this specific biomarker (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + + +clarify:existenceOf_bioAlk rdf:type owl:ObjectProperty; + rdfs:label "existenceOf_bioAlk"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Biomarker; + rdfs:comment "Whether the patient's biopsies have been studied in terms of ALK biomarker and if the result has been positive or negative in this specific biomarker (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + + +clarify:existenceOf_bioRos1 rdf:type owl:ObjectProperty; + rdfs:label "existenceOf_bioRos1"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Biomarker; + rdfs:comment "Whether the patient's biopsies have been studied in terms of ROS1 biomarker and if the result has been positive or negative in this specific biomarker (true/ false/ not studied)."; + dcterms:modified "2020-09-15"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:lastCancerStage rdf:type owl:ObjectProperty; + rdfs:label "lastCancerStage"; + rdfs:domain clarify:LCPatient; + rdfs:range clarify:Biomarker; + rdfs:comment "Representes the last known stage of the patient (I, II, III, IIIA, IIIB, IV)."; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient.ttl"; + dcterms:creator . + +clarify:hasAntiangiogenic rdf:type owl:ObjectProperty; + rdfs:label "hasAntiangiogenic"; + rdfs:domain clarify:CancerPatient; + rdfs:range clarify:Drug; + rdfs:comment "The relationship between the cancer patient and the antiangiogenic drug."; + dcterms:modified "2020-09-22"^^xsd:date; + prv:File "patient_antiangiogenicList.ttl"; + dcterms:creator . + + + + + diff --git a/clarify.txt b/clarify.txt new file mode 100644 index 0000000..7586c6d --- /dev/null +++ b/clarify.txt @@ -0,0 +1,17 @@ +# Ontology metadata attributes required for registration in the TIB ontology hub. +# This file should be maintained under the source control and must be released anongside the ontology, under the same versioning scheme. +# The file name is identical to the ontology's ttl file with .txt extension. + + +shortName: clarify +title: CLARIFYUnifiedSchema +description: A unified schema for representing data integrated in the CLARIFY knowledge graph. This schema defines the main classes and properties presented in data sources that make available genomic data, scientific publication, clinical notes, and drug interactions and the relationships among them. +autorFullName: Samaneh Jozashoori, Maria-Esther Vidal +authorEmail: samaneh.jozashoori@tib.eu, maria.vidal@tib.eu +maintainerFullname: Samaneh Jozashoori +maintainerEmail: samaneh.jozashoori@tib.eu +keywords: +license: GNU General Public License v3.0 +version: v1.0 +repositoryURL: https://github.com/tibonto/clarify # do not change this +releaseURL: https://github.com/tibonto/clarify/releases/tag/v1.0 \ No newline at end of file