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Associations between emergency procedures and outcomes in adult trauma patients

This repository includes the manuscript and code for the research project on associations between emergency procedures and outcomes in adult trauma patients.

Summary

Introduction

Trauma, the clinical entity composed of physical injury and the body’s associated response, is a massive global health threat. Reducing mortality and morbidity from trauma is part of the Sustainable Development Goals and improving trauma care is crucial to realize these goals. Trauma care is time sensitive and early interventions are key to save lives and limit suffering. The WHO has identified a set of procedures that should be performed early during trauma patient management, drawing from established trauma life support guidelines. It remains unknown to what extent these procedures are practiced, and how they associate with patient outcomes.

Aim

To assess how emergency procedures associate with outcomes in adult trauma patients

Methods

This will be a secondary analysis of data from an interrupted time series study and pilot cluster randomized controlled trial in hospitals across urban India. The participants are adult trauma patients. The sample size will be approximately 3000 patients. The student will conduct both unadjusted analyses and analyses adjusted for age, sex, mechanism of injury and trauma severity. Dichotomous outcomes will be analysed using logistic regression and continuous outcomes will be analysed using linear regression. A subgroup analysis of patients arriving within 48 hours of injury will be performed. All analyses will use a 5% significance level and 95% confidence level.

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