Home

Welcome to the wiki for the centering program! This program was designed to ensure a vertical pulling geometry for single molecule force spectroscopy measurements on made on a Cypher ES AFM (Asylum Research). In this wiki, we will provide a user guide to operate the centering program and explain general operation of the program.

See the academic paper published in ACS Nano for a full description of the science behind this program and it's scientific applications for stretching DNA, polyproteins and PEG based single-molecule force spectroscopy assays.